Probiotics: A Clinical Guide

Martin H. Floch, MD; Adam S. Kim, MD

Chapter 21: Use Of Probiotics In The Prevention And Treatment Of Radiation Enteritis (continued)

Giuseppe Famularo, MD, PhD; Vito Trinchieri, MD; Luciana Mosca, PhD; Giovanni Minisola, MD

Radiotherapy plays an important role in the treatment of abdominal and pelvic malignancies and has significantly contributed during the past decades to improved outcomes and prognoses of those patients. The potential of radiation to also cause injury to normal tissue is well understood, and this still represents an important and unresolved issue. Walsh’s first description of enteritis following abdominal exposure to radiation dates back to 1897—ie, just 2 years after the landmark discovery of X-rays.1 Technical improvements have helped reduce the frequency and severity of…