Curbside Consultation of the Pancreas: 49 Clinical Questions

Scott Tenner, MD, MPH; Alphonso Brown, MD, MS Clin Epi; Frank Gress, MD

Question 21: What Are The Complications Of Chronic Pancreatitis? (continued)

Jonathan Ari Erber, MD; Frank G. Gress, MD

Chronic pancreatitis can be associated with a variety of complications (Table 21-1). The most common include pseudocyst formation and mechanical obstruction of the duodenum or biliary tree. Other less common complications include external or internal pancreatic fistula with development of ascites or pleural effusion, splenic vein thrombosis, pseudoaneurysm formation, gastrointestinal bleeding, and cancer of the pancreas. Pseudocysts are found in 10% to 25% of patients with chronic pancreatitis and are most commonly seen in patients with alcohol-induced chronic pancreatitis.