Curbside Consultation in GI Cancer for the Gastroenterologist: 49 Clinical Questions

Douglas G. Adler, MD

Question 13: A 42-Year-Old Woman Has An Esophagogastroduodenoscopy For Dyspepsia. A 2-Cm Submucosal Lesion In The Proximal Stomach Is Seen. How Should This Lesion Be Further Evaluated And Treated? (continued)

Robert C. Wrona, MD; Robert E. Glasgow, MD

The incidence of submucosal lesions of the stomach is approximately 0.36% on routine esophagogastroduodenoscopy (EGD) performed for abdominal pain1 (Figure 13-1). The true incidence of these lesions, however, is unknown as most submucosal lesions are asymptomatic and discovered incidentally at autopsy, surgery, or during diagnostic procedures. The differential diagnosis of a submucosal lesion includes an extramural tumor, benign mesenchymal tumors (including leiomyomas, schwannomas, neurofibromas, hemangiomas, lymphangiomas, lipomas, and heterotopic pancreas), and malignant tumors (including…
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