Your patient likely has a rare condition known as hyperplastic polyposis syndrome, or HPS. The World Health Organization has established the following criteria for the diagnosis of HPS
1: (1) at least 5 hyperplastic polyps located proximal to the sigmoid colon, of which 2 are larger than 10 mm in diameter; or (2) any number of hyperplastic polyps located proximal to the sigmoid colon in an individual who has a first-degree relative with HPS; or (3) more than 30 hyperplastic polyps of any size, distributed throughout the colon. It should be noted that these criteria are somewhat arbitrary, and…