Clinical Nutrition in Gastrointestinal Disease

Alan Buchman, MD, MSPH

Chapter 5: The Malabsorption Syndrome (continued)

Robert Craig, MD

Malabsorption of nutrients can be classified by different formats; however, the most useful is in terms of the major categories “maldigestion” and “primary small intestinal absorptive defect.” Maldigestion refers to improper breaking down and solubilizing the nutrients into components that can be absorbed readily across the intestinal microvilli. Bile salts are the most important solubilizers, which allow for fat digestion and proper delivery to the small intestinal mucosa. Breaking down the macromolecules into small components is accomplished by digestive enzymes…