Clinical Nutrition in Gastrointestinal Disease

Alan Buchman, MD, MSPH

Chapter 38: Complications Of Long-Term Parenteral Nutrition (continued)

Alan L. Buchman, MD, MSPH

Most patients who require home parenteral nutrition (HPN) die from causes related to their underlying disease rather than as a complication of the parenteral nutrition (PN).1,2 Survival is 87% at 1 year for patients that have benign gastrointestinal (GI) disorders (91%, 70%, and 62% survival at 1, 3, and 5 years2) although survival for patients with nonbenign (including malignancies and radiation enteritis) GI disorders is only 10% to 50% at 1 year.1 Survival is >90% for younger patients with Crohn’s disease. PN-related complications with rehospitalization accounted for 5% of deaths…