KEY POINTS
Patients should avoid nonsteroidal anti-inflammatory drugs (NSAIDs) as much as possible, including over-the-counter varieties. If NSAIDs are needed, use the lowest possible dose and avoid multiple NSAIDs.
Smoking and alcohol increase gastric acidity and adversely affect gastroprotective mechanisms.
Zinc-based medications are effective in peptic ulcers.
Psychological interventions may be helpful in select patients. HISTORICAL PERSPECTIVE The ancient description of the use of powdered coral, chalk, and sea shells for relief of dyspepsia provides clues to the occurrence of this…