Clinical Nutrition in Gastrointestinal Disease

Alan Buchman, MD, MSPH

Chapter 32: Intestinal Transplantation (continued)

Jonathan Fryer, MD

Intestinal transplantation is a promising therapeutic alternative to long-term parenteral nutrition (PN) for patients with intestinal failure. The complex interactions between the intestinal graft, the recipient immune system, and the external environment have made successful transplantation a significant challenge. While outcomes with early intestinal transplant efforts were sub-optimal, recent results reveal significant improvements in graft and patient survivals. Ongoing basic research, combined with the increased clinical experience and careful selection of patients, will be necessary to…