Curbside Consultation in IBS: 49 Clinical Questions

Brian E. Lacy, PhD, MD

Question 31: What is the Relationship between Fructose Intolerance and IBS? (continued)

Fernando Fernández-Bañares, MD, PhD

Malabsorption of sugars (lactose, fructose, and/or sorbitol) from a normal diet may induce chronic abdominal discomfort in sensitive individuals, including abdominal dis-tension, flatulence, cramps, and diarrhea. There may be an intrasubject and intersubject variability in the threshold leading to gastrointestinal distress after ingestion of incompletely absorbed carbohydrates.1 Whether sugar malabsorption will cause symptoms depends on several factors besides the absorptive capacity, such as the quantity and quality of the ingested carbohydrate load, the time spent to consume, and the…