Clinical Nutrition in Gastrointestinal Disease

Alan Buchman, MD, MSPH

Chapter 17: Nutrition And Colorectal Cancer (continued)

Young-In Kim, MD, FRCP(C)

The development of colorectal cancer (CRC) is thought to be the result of an intimate, and yet poorly understood, interplay between environmental and genetic factors. CRC incidence rates vary approximately 10- to 200-fold across different geographic locations around the world, with the highest observed in the developed, westernized, industrialized, and urbanized parts of the world.1 The international differences, migrant data, and recent rapid increases in incidence rates in the same geographic location with previously low CRC incidence rates over time collectively suggest that environmental…