KEY POINTS

Melatonin is an important regulator of both inflammation and motility in the GI tract.

Preliminary data indicate a potential benefit in ulcerative colitis and irritable bowel syndrome (IBS).
1,2,3 Melatonin is one of the most versatile and ubiquitous hormonal molecules in the body and is associated with numerous metabolic functions, circadian rhythm, and wake-sleep cycle.
4,5 ACTIONS OF MELATONIN FOR HEALTHY GUT

Melatonin is an important regulator of…