Clinical Nutrition in Gastrointestinal Disease

Alan Buchman, MD, MSPH

Chapter 20: Nutrition And Liver Disease (continued)

Marwan Ghabril, MD; Jaime Aranda-Michel, MD

The liver is the largest metabolic organ in the human body, fulfilling critical roles in the metabolism of a variety of nutrients that are essential to maintaining the integrity and adequate physiologic function of multiple organ systems and the body as a whole. Severe hepatic impairment leads to a broad spectrum of metabolic derangements, which lead to protein-energy malnutrition, which significantly impacts clinical outcomes. Better recognition of this correlation has led to an increased interest in better delineating the relationship, establishing a recognized standard of measuring…