KEY POINTS

While many of the reports of herbal-induced hepatotoxicity are very well documented, some have been implicated solely based on occasional case reports—without rigorous medical scrutiny.

Best data available from the United States implicate herbal-induced hepatotoxicity in less than 10% of all drug-induced liver toxicity. Concerns continue to be raised about potential hepatotoxicity from herbal therapies, sometimes bordering on hysteria. While such implications are clearly justified, many times the evidence may not meet the established criteria,
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