GI and Liver Disease During Pregnancy: A Practical Approach

Kim L Isaacs, MD PhD; Millie D Long, MD MPH

Chapter 12: Acute Liver Disease (continued)

Eric S. Orman, MD; A. Sidney Barritt IV, MD, MSCR

Acute liver injury (ALI) occurs uncommonly during pregnancy, with an estimated incidence of 3%.1 Despite its rarity, awareness of acute liver dysfunction is important due to its associated morbidity and mortality. Furthermore, prompt recognition and identification of a specific etiology is important because early and specific intervention may improve patient outcomes (eg, anticoagulation for Budd-Chiari syndrome or early delivery for acute fatty liver of pregnancy). Acute liver disease can be categorized into 2 groups: general liver diseases that occur coincidentally during a pregnancy, and…