Gut Instincts: A Clinician's Handbook of Digestive and Liver Diseases

Eric Esrailian, MD, MPH

Chapter 36: Alcoholic Liver Disease (continued)

Saro Khemichian, MD; John A. Donovan, MD

Two-thirds of American adults drink some amount of alcohol. A subgroup tends to drink excessively, and this may lead to a number of alcohol-related conditions including alcoholic liver disease (ALD). ALD does not necessarily follow a dose-dependent progression. Only a subset of heavy drinkers develop liver disease. Certain risk factors have been identified that promote the development and progression of ALD (Table 36-1). The amount of alcohol ingested is among the most important of these risk factors. The risk of developing alcoholic cirrhosis increases with ingestion of more than 60 to 80…