Johns Hopkins Manual for GI Endoscopic Nurses, Third Edition

Mouen Khashab, MD; Toshunia Robinson, MD; Anthony Kalloo, MD

Chapter 41: Endoscopic Pancreatic Function Testing (continued)

Vikesh K. Singh, MD, MSc

Direct methods to assess pancreatic exocrine function have been used for decades. This was previously done using a double lumen gastroduodenal tube (Dreiling tube). The gastric lumen was used to aspirate gastric fluid and the duodenal lumen was used to aspirate pancreatic fluid. Secretin was administered to assess bicarbonate concentration as a measure of pancreatic duct cell function and cholecystokinin (CCK) was administered to assess digestive enzyme concentrations as a measure of pancreatic acinar cell function. Upper endoscopy has replaced the use of the Dreiling tube for timed…
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