Johns Hopkins Manual for GI Endoscopic Nurses, Third Edition

Mouen Khashab, MD; Toshunia Robinson, MD; Anthony Kalloo, MD

Chapter 14: EGD With Cryotherapy (continued)

Marcia Irene Canto, MD, MHS

Also called cryoablation, cryotherapy is the application of extreme cold to the GI mucosa with either a high pressure device using nitrous oxide gas or a low pressure device using liquid nitrogen at ambient pressure. Cryoablation is performed to destroy the dysplasia and superficial early carcinoma in Barrett’s esophagus, provide hemostasis of GI bleeding (ie, watermelon stomach), and palliation of esophageal and gastric neoplasms. The freezing of the tissue allows destruction of the tissue while preserving the underlying collagen tissue to provide a scaffold for healthy tissue to grow…