Johns Hopkins Manual for GI Endoscopic Nurses, Third Edition

Mouen Khashab, MD; Toshunia Robinson, MD; Anthony Kalloo, MD

Chapter 30: Chromoendoscopy (continued)

Christina Ha, MD

Chromoendoscopy (Figure 30-1) involves the topical application of dyes to alter tissue appearance and improve localization, characterization, and diagnosis of dysplastic mucosal lesions (such as Barrett’s esophagus or colon neoplasias). Chromoendoscopy usually adds 5 to 10 minutes to the endoscopic procedure. Lugol’s solution stains normal squamous cells of the esophagus brownish-black or greenish-brown within moments and gradually fades in a couple of hours. Abnormal cells do not stain. The technique is useful to detect high-grade dysplasia and early squamous cell cancers of the…
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