Curbside Consultation in Endoscopy: 49 Clinical Questions, Second Edition

Joseph Leung, MD; Simon Lo, MD

Question 21: What Is The Role Of Chromoendoscopy In Screening Colonoscopy? Will It Help To Differentiate Different Types Of Polyps, And Is It Useful For Proximal Serrated Polyps? (continued)

Charles J. Kahi, MD, MSc; Ihab I. El Hajj, MD, MPH

Dye-based colonoscopy with chromoendoscopy (CE), or chromocolonoscopy, consists of pancolonic or lesion-targeted application of absorptive or contrast stains to an adequately cleansed colonic mucosa. This can be done using a special spray catheter during conventional white light colonoscopy. CE is inexpensive, safe, and relatively straightforward to learn and perform for an endoscopist who is already experienced in conventional colonoscopy. The superficial structure of lesions is enhanced by active mucosal uptake of dye (absorptive stains) or by the pooling of dye in colonic pits and ridges…