Johns Hopkins Manual for GI Endoscopic Nurses, Third Edition

Mouen Khashab, MD; Toshunia Robinson, MD; Anthony Kalloo, MD

Chapter 5: Endoscopy In Patients With Specific Medical Problems (continued)

Mouen A . Khashab, MD

Antibiotic prophylaxis for gastrointestinal endoscopic procedures are described in Table 5-1. One acceptable antibiotic prophylaxis regime consists of intravenous ampicillin 2 g and gentamicin 1.5 mg/kg (up to 80 mg) 30 minutes prior to the endoscopic procedure, followed by amoxicillin 1.5 g orally 6 hours after the procedure. For penicillin-sensitive patients, vancomycin or clindamycin may be substituted. Patients undergoing percutaneous gastrostomy tube placement should receive cefazolin 1 g 30 minutes prior to the procedure. If, however, these patients are already on an equivalent…
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