Curbside Consultation in Endoscopy: 49 Clinical Questions, Second Edition

Joseph Leung, MD; Simon Lo, MD

Question 33: A 48-Year-Old Male Had Liver Transplantation 9 Months Ago For Chronic Hep C Cirrhosis. He Presented Recently With Recurrence Of Jaundice And Impaired Lfts. How Should I Manage This Patient? (continued)

Milan Bassan, MBBS, FRACP; Paul Kortan, MD, FRCPC, FASGE, AGAF

Recurrent jaundice and derangement of liver function tests (LFTs) following liver transplantation can have a number of possible causes. The initial step in the management is to determine whether the hepatic disturbance is related to parenchymal pathology (such as recurrence of hepatitis C, chronic rejection, or drug-induced liver injury) or biliary pathology. This chapter will focus on the management of posttransplant biliary disease. When faced with a patient who potentially has significant posttransplant biliary pathology that is causing jaundice, the first step is a thorough clinical…