Curbside Consultation in Endoscopy: 49 Clinical Questions, Second Edition

Joseph Leung, MD; Simon Lo, MD

Question 47: In True Obscure Gi Bleeding, What Should I Do If A Capsule Endoscopy And Upper And Lower Endoscopies Are Unrevealing? (continued)

Anupam Singh, MD; David R. Cave, MD, PhD

Obscure gastrointestinal bleeding (OGIB) is defined as bleeding from the gastrointestinal (GI) tract that persists or recurs without an obvious etiology after an upper endoscopy and colonoscopy. It accounts for approximately 5% of all GI bleeding and identifying a source can be time intensive and frustrating for both the clinician and the patient. OGIB is further classified as obscure occult or obscure overt bleeding. Obscure overt bleeding manifests as visible blood (hematochezia or melena), whereas obscure occult bleeding manifests as a positive fecal occult blood test or iron…