Gut Instincts: A Clinician's Handbook of Digestive and Liver Diseases

Eric Esrailian, MD, MPH

Chapter 21: Irritable Bowel Syndrome (continued)

Emeran A. Mayer, MD

Irritable bowel syndrome (IBS), characterized by chronically recurring abdominal pain or discomfort and altered bowel habits, is one of the most common syndromes seen by gastroenterologists and primary-care providers, with a worldwide prevalence of 10% to 15%. In the absence of detectable organic causes, IBS is currently referred to as a functional or symptom-based syndrome, which is defined by symptom criteria (see the ROME criteria in Table 21-1). IBS is one of several functional gastrointestinal (GI) disorders (including functional dyspepsia), and these other functional disorders are…