Curbside Consultation in IBS: 49 Clinical Questions

Brian E. Lacy, PhD, MD

Question 21: What is the Role of Bacterial Overgrowth in IBS Patients? (continued)

Mark Pimentel, MD

Irritable bowel syndrome (IBS) is a chronic condition that is diagnosed using a characteristic group of symptoms. The symptoms that define IBS include abdominal pain, bloating, and an altered pattern of bowel habits (constipation, diarrhea, or both). Although this condition is one of the most common disorders seen in clinical practice, the cause of these symptoms remains unknown. A great deal of research has focused on the role of stress and serotonin in the generation of IBS symptoms. Interestingly, however, the symptom of bloating has been largely ignored in clinical trials, despite the…