Curbside Consultation in IBD: 49 Clinical Questions, Second Edition

David T Rubin, MD; Sonia Friedman, MD; Francis A Farraye, MD MSc

Question 2: How Can I Clarify The Diagnosis In My Patient With Indeterminate Colitis? (continued)

William J. Tremaine, MD

The terminology for indeterminate colitis (IC) is controversial. Although IC is commonly used by clinicians for patients who have features of both Crohn’s colitis and ulcerative colitis, it has been proposed that the term inflammatory bowel disease unclassified (IBDU) should be used for those patients and a diagnosis of IC should be made only after colectomy.1 For this discussion, IC includes both IBDU and postcolectomy patients. As clinicians, we assume that a patient with IC has either Crohn’s disease (CD) or ulcerative colitis (UC), and our inability to make a definitive…