Crohn's Disease: The Complete Guide to Medical Management

Gary R. Lichtenstein, MD, FACP, FACG, AGAF

Chapter 5: Pediatric Considerations in Medical Therapy in Patients with Inflammatory Bowel Disease (continued)

Louis R. Ghanem, MD, PhD; Robert N. Baldassano, MD

Although the similarities between adult and pediatric patients diagnosed with IBD are numerous, several important differences should be emphasized. In addition to the usual gastrointestinal symptoms of diarrhea, abdominal pain, and rectal bleeding, children may exhibit prominent extraintestinal manifestations, such as growth failure, weight loss, anemia, delayed puberty, and joint symptoms. Other problems unique to pediatrics include the lack of appropriate numbers of controlled clinical trials and the psychological issues that occur in children and adolescents with IBD. These unique problems…