Ulcerative Colitis: The Complete Guide to Medical Management

Gary R. Lichtenstein, MD, FACP, FACG, AGAF

Chapter 7: Disease Modifiers in Inflammatory Bowel Disease (continued)

Jaime A. Oviedo, MD; Francis A. Farraye, MD, MSc, FACP, FACG

DISEASE MODIFIERS IN INFLAMMATORY BOWEL DISEASE Although the individual susceptibility to develop inflammatory bowel disease (IBD) appears to be genetically determined, the actual occurrence of the disease is largely influenced by environmental factors. Though extraordinary advances have been made in our understanding of the genetics, pathogenesis, diagnosis, and medical management of patients with IBD, our emphasis on environmental modifiers, health maintenance, and lifestyle factors that can affect the course, complications, and severity of the disease has not been nearly as significant…