Clinical Challenges and Complications of IBD

Miguel D Regueiro, MD; Jason Swoger, MD MPH

Chapter 13: Vaccination And Immunization Issues For Patients With IBD (continued)

Gil Y. Melmed, MD, MS

The mainstay of medical therapy for patients with inflammatory bowel disease (IBD) increasingly involves the use of immunosuppression, including corticosteroids, immunomodulators, and biologic therapies. The most common adverse events associated with immunosuppressive therapies are infections, including vaccine-preventable diseases.1,2 Patients with IBD are at an increased risk for infection, not only due to immunosuppressive therapies, but also due to malnutrition, hospitalization, and surgery. Many infections are preventable with prophylactic immunizations. Furthermore, some infections can…