Curbside Consultation in IBD: 49 Clinical Questions, Second Edition

David T Rubin, MD; Sonia Friedman, MD; Francis A Farraye, MD MSc

Question 33: What Is The Best Medical Therapy For Inflammatory Bowel Disease In Elderly Patients? Are Anti-Tumor Necrosis Factors Safe In This Patient Population? (continued)

Darrell S. Pardi, MD; Edward V. Loftus Jr, MD

Although inflammatory bowel disease (IBD) is generally considered a condition of young adults, 10% to 15% of patients are older than 60 years of age at the time of diagnosis. Of these older patients, the majority are diagnosed in their 60s (65%), with fewer in their 70s (25%) and 80s (10%). Accurately determining the incidence of IBD in elderly patients can be challenging due to confusion with other diagnoses, including infectious and ischemic. In population-based cohort studies, the incidence of Crohn’s disease (CD) in patients over age 60 is 3 to 11…