Clinical Challenges and Complications of IBD

Miguel D Regueiro, MD; Jason Swoger, MD MPH

Chapter 10: Hepatobiliary Disease (continued)

Mark E. Gerich, MD; Edward V. Loftus Jr, MD

The interaction between inflammatory bowel disease (IBD) and liver disease was first described more than 100 years ago.1 Although previously believed to be rare, hepatobiliary disease in IBD is now recognized as one of the more common extraintestinal manifestations of IBD.2-4 The exact prevalence of hepatobiliary disease in IBD is difficult to assess because of variability across studies in the definition of hepatobiliary dysfunction, diagnostic aggressiveness, and the patient cohorts that were studied.3 For instance, when transient elevation…