Common Liver Diseases and Transplantation: An Algorithmic Approach to Work Up and Management

Robert S Brown Jr, MD MPH

Chapter 7: Hepatitis C Virus (continued)

Elizabeth C. Verna, MD, MS; Robert S. Brown Jr, MD, MPH

Hepatitis C virus (HCV) is among the most common chronic infections in the world. Approximately 170 million people worldwide and over 3 million people in the United States are currently chronically infected. Unfortunately, the majority of patients with chronic HCV are unaware that they have the disease. The majority (55% to 85%) of people exposed to HCV will suffer from chronic infection, and roughly 10% to 20% of these patients will develop life-threatening sequelae including cirrhosis and hepatocellular carcinoma. Therefore, HCV remains the leading indication for liver transplantation in…