Curbside Consultation in GERD: 49 Clinical Questions

Philip O. Katz, MD

Question 28: Are The Pharmacologic Options For Barrett’S Different From Gerd? Have Ppis Been Shown To Have Any Effect On Barrett’S (Either Prevention Or Therapy)? (continued)

The primary controversy in Barrett’s esophagus relates to what form of therapy is “best” and, more importantly, whether any therapy results in the regression of abnormal epithelium or more importantly reduces the rate of progression to dysplasia and/or adenocarcinoma. The current standard of practice suggests that patients with Barrett’s should be treated in similar fashion to patients with typical GERD, that is with antisecretory agents as needed to provide complete symptom relief. The most recent American College of Gastroenterology (ACG) guidelines point out…