Curbside Consultation in GERD: 49 Clinical Questions

Philip O. Katz, MD

Question 36: What Is The Role Of Helicobacter Pylori In Gerd? Do All Patients With Gerd Need To Be Tested For Helicobacter Pylori? (continued)

Helicobacter pylori is a gram-negative, spiral, flagellated organism that infects the gastric mucosa, leading to chronic gastritis. It has been causally related to duodenal and gastric ulcers, gastric cancer, and gastric mucosa associated lymphoid tissue (MALT) lymphoma. It has been linked to the increased risk for development of ulcer disease in patients on nonsteroidal anti-inflammatory drugs and as a potential contributor to functional or nonulcer dyspepsia. There are three patterns of infections. Chronic active antral gastritis results in an increase in gastric acid secretion and…