Curbside Consultation in IBS: 49 Clinical Questions

Brian E. Lacy, PhD, MD

Question 39: What is the Role of Antidiarrheal Agents in Patients with IBS? (continued)

Lawrence R. Schiller, MD, FACP, FACG

In the absence of a cure, mitigation of symptoms is the goal of treatment in irritable bowel syndrome (IBS) patients. For patients with IBS with diarrhea, treatment of diarrhea becomes an important management endpoint.1,2 This is particularly true when diarrhea is accompanied by urgency of defecation or frank fecal incontinence, features that substantially increase the severity of the condition. Physicians should always remember that diarrhea in IBS can be triggered by environmental issues, such as diet and stress. If possible, these problems should be identified and managed; drug therapy…