Crohn's Disease: The Complete Guide to Medical Management

Gary R. Lichtenstein, MD, FACP, FACG, AGAF

Chapter 17: Infliximab in Crohn's Disease (continued)

Lawrence W. Comerford, MD; Stephen J. Bickston, MD, AGAF

CD is a chronic inflammatory disorder of the gastrointestinal tract that results in significant morbidity and health-care expenditure. More than 400,000 individuals in the United States have been diagnosed with CD, and the prevalence continues to increase as a result of both increasing incidence and improved survival.1 The chronic nature of CD results in frequent hospitalizations, with a majority of patients eventually requiring surgery as a result of complications such as strictures, abscesses, fistula, or refractory disease. The etiology of CD is currently unknown, but the disease…