Managing the Complications of Cirrhosis: A Practical Approach

Atif Zaman, MD, MPH

Chapter 5: Management Of Ascites And Renal Issues In Patients With Cirrhosis (continued)

Jonathan M. Fenkel, MD; Victor J. Navarro, MD

Ascites is the most common complication of cirrhosis, and 50% of patients with cirrhosis will develop ascites within 10 years of diagnosis.1 It can usually be managed effectively with a combination of diuretics and salt restriction. Occasionally, other therapies are necessary, which will be discussed in this chapter. Once ascites develops, it should clue the clinician in to the possibility that a patient may require liver transplantation, because there is an estimated 50% mortality at 2 years from its onset.2 Hepatorenal syndrome (HRS) is a discrete form of renal failure occurring in…