Atopic Dermatitis/Skin Diseases
The skin of children with early-onset atopic dermatitis exhibits significantly different phenotypes when compared with the skin of adults with a long-standing history with the disease, according to research published in The Journal of Allergy and Clinical Immunology.
“It is important to recognize the differences in phenotypes between children and adults because different or additional therapeutics may be more suited to children or adults,” Emma Guttman, MD, PhD, vice chair of the department of dermatology at the Icahn School of Medicine at Mount Sinai, told Infectious Diseases in Children. “While the TH2 axis is activated in both children and adults, the TH17 axis is increased primarily in children, similar to psoriasis. Perhaps psoriasis-focused treatments can be applicable to children with atopic dermatitis.”
This activity is supported by an educational grant from Genentech, Inc.
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