Allergic Disease Mechanisms

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Skin patch for peanut allergy yields higher immunity in children

December 22, 2016

Children were able to overcome allergic response to peanuts by wearing a skin patch that administered epicutaneous immunotherapy in the form of peanut protein, according to clinical trial findings published in the Journal of Allergy and Clinical Immunology.

“To avoid potentially life-threatening allergic reactions, people with peanut allergy must be vigilant about the foods they eat and the environments they enter, which can be very stressful,” National Institute of Allergy and Infectious Diseases director Anthony S. Fauci, MD, said in a press release. “One goal of experimental approaches such as epicutaneous immunotherapy is to reduce this burden by training the immune system to tolerate enough peanut to protect against accidental ingestion or exposure.”

In the JournalsPerspective

Infants’ peanut consumption found safe for future growth, nutrition

July 6, 2016
Recent data suggested that early-life peanut consumption, as part of a strategy that reduces peanut allergy risk, was nutritionally safe and did not interfere with…
In the Journals

Quilizumab appears tolerable, reduces serum IgE levels

April 25, 2016
Patients in this study who received quilizumab had reduced serum immunoglobulin E levels and appeared to tolerate the humanized IgG1 monoclonal antibody well, according…
In the Journals

Novel IRF2BP2 mutation linked to CVID–like immunodeficiency

April 15, 2016
Researchers identified a novel mutation in IRF2BP2 in a family with a history of common variable immunodeficiency disorder, which may be the cause of the disease…
In the Journals

Food allergy in adolescents linked to emotional, behavioral problems

February 25, 2016
Adolescents with food allergies are also more likely to have emotional and behavioral problems such as attention deficit hyperactivity disorder…

In the Journals

Allergic diseases at age 4 predict increased risk for developing internalizing behaviors at age 7

January 13, 2016
Young patients with allergic diseases such as allergic rhinitis and allergic persistent wheezing are significantly more likely to develop…

Meeting News Coverage

Siblings of allergic children often show food sensitivities not allergies

November 6, 2015
SAN ANTONIO — Siblings of children with food allergies were likely to have food sensitivity, but not likely to have the same food allergies…

In the Journals

Tobacco smoke, IgE sensitization leaves children susceptible to environmental allergens

October 29, 2015
Children exposed to tobacco smoke may have altered immunoglobulin E–mediated immune responses that may make them more sensitive to…

In the Journals

Novel SNPs identified for bone mineral accretion in children

June 24, 2015
Two novel tubulin pathway single nucleotide polymorphisms were associated with independent interactive effects of cumulative corticosteroid dose on…

In the Journals

Algorithm for CRS classification may predict recurrence risk, refractoriness

June 23, 2015
A diagnostic algorithm for classifying chronic rhinosinusitis demonstrated utility in determining refractoriness and recurrence risk for the…

In the Journals

Urbanization affects development of allergen sensitization among elderly

April 13, 2015
Urbanization was linked with self-reported rhinitis symptoms and sensitization to inhalant allergens in an elderly South Korean population, according…

In the Journals

Breast-feeding does not affect allergy sensitization in children

April 10, 2015
The time a mother spends breast-feeding her child has no impact on the development of allergy sensitization in children at high risk for developing…

Meeting News Coverage

Tiotropium improves lung function in asthma, regardless of allergic status

February 26, 2015
HOUSTON — The addition of tiotropium Respimat in adult patients with mild, moderate and severe asthma improved lung function independent of…

Meeting News CoverageVideo

VIDEO: 3 things to know from AAAAI 2015

February 22, 2015
HOUSTON — Mary Beth Fasano, MD, FAAAAI, vice chair of the annual meeting programming committee, spoke to about key…

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