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Infusion of bupivacaine with epinephrine associated with development of knee chondrolysis

Infusion of bupivacaine with epinephrine associated with development of knee chondrolysis
April 20, 2015

Patients who received intra-articular infusion of bupivacaine with epinephrine postoperatively after arthroscopic ACL reconstruction were at risk for developing knee chondrolysis, according to study results.

Researchers reviewed the charts of all patients treated with arthroscopic ACL reconstruction between January 2004 and December 2006. Forty-six patients were included in the exposure group and received postoperative infusion of bupivacaine with epinephrine through an intra-articular pain pump, and 59 patients were part of a control group and did not receive postoperative infusion.

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