Juvenile Arthritis

Top Story

Researchers compare CCP profile of patients with JIA vs RA

April 26, 2017

Among patients with rheumatoid arthritis and patients with a polyarticular subtype of juvenile idiopathic arthritis, researchers at University College London compared profiles of antibodies to cyclic citrullinated peptide profiles.

“[This] study has demonstrated the novel finding that adolescent [rheumatoid factor-positive polyarticular juvenile idiopathic arthritis] pJIA (RF+ve) patients are distinct in their anti-[cyclic citrullinated protein] CCP antibody phenotype from other JIA clinical patterns and age/sex matched healthy controls; but are comparable to adult RF-positive patients in their levels of IgG anti-CCP and shared expression of the same inherently autoreactive 9G4 idiotype,” Yiannis Ioannou, PhD, at the Arthritis Research UK Centre for Adolescent Rheumatology at University College London, and colleagues wrote. “However, it was found that the adult group had significantly higher levels of IgA and IgM anti-CCPs than the adolescent group, suggesting that further investigation is needed to fully elucidate the extent to which these two conditions may be seen as one.”

Biosimilars to rituximab, etanercept recommended for approval in Europe

April 21, 2017
The Committee for Medicinal Products for Human Use has recommended approval of biosimilars by Sandoz for rituximab and etanercept for the same indications as the…
In the Journals

Study: Published criteria to identify inactive JIA do not always overlap

April 20, 2017
Published criteria to identify inactive disease or low disease activity do not always identify the same patients, according to a recently published study. “The…
In the Journals

Higher rates of complications after THA found among patients with inflammatory arthritis

April 17, 2017
Patients with inflammatory arthritis who underwent total hip arthroplasty experienced higher rates of complications compared with patients who had osteoarthritis…
CME

Timing of Tourniquet Release in Total Knee Arthroplasty: July 2015

The authors conducted a meta-analysis to determine the optimal tourniquet application strategy in total knee…
More »
Video
Meeting News Coverage

VIDEO: Mamaras highlights CreakyJoints' patient advocacy

November 27, 2015
More »
Featured
Osteoarthritis Research Society International World Congress

Osteoarthritis Research Society International World Congress

CME

Hip Resurfacing Implants: August 2015

Hip resurfacing offers a suitable solution for young patients affected by hip disease who have high function demands…
More »
In the Journals

Researchers compare CCP profile of patients with JIA vs RA

April 26, 2017
Among patients with rheumatoid arthritis and patients with a polyarticular subtype of juvenile idiopathic arthritis, researchers at University…

Biosimilars to rituximab, etanercept recommended for approval in Europe

April 21, 2017
The Committee for Medicinal Products for Human Use has recommended approval of biosimilars by Sandoz for rituximab and etanercept for the same…

In the Journals

Study: Published criteria to identify inactive JIA do not always overlap

April 20, 2017
Published criteria to identify inactive disease or low disease activity do not always identify the same patients, according to a recently published…

In the Journals

Higher rates of complications after THA found among patients with inflammatory arthritis

April 17, 2017
Patients with inflammatory arthritis who underwent total hip arthroplasty experienced higher rates of complications compared with patients who had…

In the Journals

Etanercept, adalimumab linked with increased infection risk vs methotrexate for JIA

April 4, 2017
Investigators found a slightly increased risk for serious infection among patients with juvenile idiopathic arthritis who took first-line etanercept…

European Commission approves adalimumab biosimilar for treatment of RA, PsA, AS, JIA

March 27, 2017
The European Commission has approved Amgevita, a biosimilar to adalimumab, for the treatment of moderate to severe rheumatoid arthritis, psoriatic…

In the Journals

Uveitis linked with reduced vision-related quality of life in adulthood for patients with JIA

March 7, 2017
A history of uveitis had a negative effect on vision-related quality of life in adulthood for patients with juvenile idiopathic arthritis, according…

In the Journals

Etanercept/methotrexate best of three treatments in juvenile idiopathic arthritis

February 10, 2017
Compared with sulfasalazine monotherapy or methotrexate with initial prednisone bridging, etanercept and methotrexate combination therapy was…

In the Journals

Model estimates likelihood of severe disease in patients with JIA

February 6, 2017
Researchers have developed a prediction model to estimate the likelihood of severe disease in patients diagnosed with juvenile idiopathic arthritis…

In the JournalsPerspective

Half of children with JIA in study had sleep apnea

January 24, 2017
In a study of 68 children with juvenile idiopathic arthritis, about half had obstructive sleep apnea, according to recently published results…

More Headlines »
Advertisement
Advertisement