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Compared with MTX, TNF inhibitor monotherapy, combination therapy did not increase infection risk in JIA

Compared with MTX, TNF inhibitor monotherapy, combination therapy did not increase infection risk in JIA
September 30, 2016

Compared with methotrexate monotherapy, tumor necrosis factor inhibitor monotherapy or used in combination with methotrexate were not associated with an increased risk for infection in patients with juvenile idiopathic arthritis, according to recently published findings.

“Neither [tumor necrosis factor inhibitor] TNFi monotherapy nor TNFi plus methotrexate combination therapy were associated with an increased risk of infection compared to methotrexate,” Tim Beukelman, MD, MSCE, in the Division of Pediatric Rheumatology at the University of Alabama at Birmingham, told Healio Rheumatology.

In the Journals

Severe knee pain linked with less willingness to undergo TKR among uninsured patients

September 30, 2016
Among the uninsured, severe knee pain was associated with less willingness to undergo a total knee replacement, according to recently published findings. “Despite…

Revised AAOS position statement focuses on prevention of subsequent fractures

September 30, 2016
The board of directors of the American Academy of Orthopaedic Surgeons has approved a revised position statement that notes physicians should screen, monitor and help…
In the Journals

Majority of adverse events in clinical trials remain unpublished

September 30, 2016
A lower number and smaller range of adverse events were reported in published studies compared with those unpublished, according to data published in PLoS Medicine
In the Journals

Allopurinol use reduced risk for myocardial infarction in Medicare beneficiaries

September 29, 2016
Allopurinol use reduced the risk of myocardial infarction in Medicare beneficiaries, according to recently published data. In addition, longer durations of allopurinol…
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CME

The Patient with Back Pain

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Back pain is a common disorder, with nearly 80% of adults experiencing lower back pain over the course of their…
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Video

VIDEO: Cush addresses management of methotrexate use in patients with RA

August 12, 2016
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Rheumatology Nurses Society Annual Conference

Rheumatology Nurses Society Annual Conference

CME

Unipolar Versus Bipolar Hemiarthroplasty for Displaced Femoral Neck Fractures in Elderly Patients: November 2015

Hip replacement using hemiarthroplasty (HA) is a common surgical procedure in elderly patients with femoral neck…
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