Violence/Trauma

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Gene may predict PTSD severity, abnormal brain functions related to emotions, coping

September 4, 2015

The spindle and kinetochore-associated complex subunit 2 gene may be a predictor of PTSD symptoms and cortical thinning in brain regions that regulate strong emotions and coping with stress, according to study findings in Molecular Psychiatry.

“Building on previous research on [spindle and kinetochore-associated complex subunit 2 (SKA2)], the primary aims of this study were to examine whether SKA2 methylation is associated with alterations in cortical thickness and suicide-related psychiatric symptoms, specifically PTSD and depression. We focused on cortical rather than subcortical structures (for example, hippocampus), based on evidence of reduced expression of SKA2 in prefrontal tissue of suicide patients,” the researchers wrote. “Based on evidence that the SKA2 protein may be involved in mitigating the neurotoxic effects of stress, we hypothesized that greater DNA methylation of the cytosine-guanine site identified by Guintivano, et al would be associated with decreased cortical thickness in prefrontal brain regions.”

Louis Appleby, MD In the Journals

Psychiatric disorders may increase risk for violent reoffending among prisoners

September 3, 2015
Data from a longitudinal study cohort of prisoners indicated an association between increased risk for violent reoffending and diagnosed psychiatric disorders…
In the Journals

Rate of psychotropic drug prescription far exceeds rate of mental illness in the UK

September 2, 2015
In the UK, individuals with intellectual disabilities and a history of challenging behavior are often prescribed psychotropic drugs, despite not having any record of…
In the JournalsPerspective

Obstructive sleep apnea worsens symptoms, QOL in patients with PTSD

August 28, 2015
Patients with combat-related PTSD who also had obstructive sleep apnea demonstrated worsened sleep-related symptoms and quality of life compared with patients without…
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Rampage Murderers, Part I: Psychotic Versus Non-Psychotic and a Role for Psychiatry in Prevention

Psychiatric Annals, May 2014, Volume 44 Issue 5
Mass murders are horrific tragedies that gain intense media coverage; they do not seem rare any more. In the U.S…
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CME
Psychiatry Case Consults

The Patient with Bipolar Disorder

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This CME activity will focus on the diagnosis and management of patients with bipolar disorder.
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Meeting News Coverage Video
VIDEO: Physical, mental challenges of deployed female soldiers

VIDEO: Physical, mental challenges of deployed female soldiers

May 22, 2015
TORONTO — Elspeth "Cam" Ritchie, MD, MPH, a forensic psychiatrist and former chief clinical officer for the…
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In the Journals

Gene may predict PTSD severity, abnormal brain functions related to emotions, coping

September 4, 2015
The spindle and kinetochore-associated complex subunit 2 gene may be a predictor of PTSD symptoms and cortical thinning in brain regions that…
Louis Appleby, MD In the Journals

Psychiatric disorders may increase risk for violent reoffending among prisoners

September 3, 2015
Data from a longitudinal study cohort of prisoners indicated an association between increased risk for violent reoffending and diagnosed psychiatric…
In the Journals

Rate of psychotropic drug prescription far exceeds rate of mental illness in the UK

September 2, 2015
In the UK, individuals with intellectual disabilities and a history of challenging behavior are often prescribed psychotropic drugs, despite not…
In the JournalsPerspective

Obstructive sleep apnea worsens symptoms, QOL in patients with PTSD

August 28, 2015
Patients with combat-related PTSD who also had obstructive sleep apnea demonstrated worsened sleep-related symptoms and quality of life compared with…
Katie A. McLaughlin, PhD In the Journals

Strategies to regulate emotion effective among maltreated children

August 26, 2015
When given strategies to regulate emotions, adolescents who experienced maltreatment were able to modulate their emotional responses when viewing…
In the Journals

Attention bias variability may be useful biomarker of PTSD

August 21, 2015
Attention bias variability may be a useful cognitive biomarker of PTSD, according to study findings in the American Journal of
In the Journals

Recurrent PTSD, traumatic brain injury associated with similar weakened brain connectivity

August 17, 2015
Analysis of MRI data indicated a relationship between re-experiencing PTSD symptoms and weakened connectivity in a brain network involved in…
Filip K. Arnberg, PhD In the Journals

Tsunami exposure may have lasting effects on mental well-being of survivors

August 11, 2015
Swedish adults repatriated by a Southeast Asian tsunami in 2004 had higher risk for stress-related disorders and attempted suicide compared with…
In the Journals

Childhood physical, sexual abuse associated with increased risk for developing ulcerative colitis

August 10, 2015
Adults who were physically or sexually abused during childhood had an estimated twofold increased risk for developing ulcerative colitis, according…
Scott Hadland, MD, PhD In the Journals

Attempted suicide, childhood maltreatment common among youth living, working on streets

August 6, 2015
Self-reported attempted suicide and childhood maltreatment were common among children living or working on the street in Vancouver, Canada…
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