March 28, 2017
Longitudinal analysis indicated associations between extended use of stimulant medications and shorter adult height but not symptom reduction.
“The [Multimodal Treatment Study] began as a 14-month randomized clinical trial to test hypotheses about four treatment strategies: medication management, behavior modification, their combination, or treatment-as-usual for a community comparison,” James M. Swanson, PhD, of University of California, Irvine, and colleagues wrote. “After the [randomized clinical trial], the [Multimodal Treatment Study] transitioned into an observational long-term follow-up, and analyses were performed to generate hypotheses for future studies. At 2, 3, and 8 years after baseline, [intention-to-treat] analyses of the randomly assigned groups were continued and indicated the initial symptom-related benefit and growth-related cost dissipated after the 14-month treatment-by-protocol phase.”