July 25, 2016
Reduced reward positivity predicted first-onset depressive disorder among adolescent girls, suggesting blunted neural response may be an important target for screening and prevention.
“Adolescence is a high-risk period for the emergence of depression. Prospective studies show a marked increase in rates of depression from childhood through adolescence, and epidemiological studies indicate that the lifetime prevalence of depression in adolescence is approximately 11% to 14%,” Brady D. Nelson, PhD, of Stony Brook University, New York, and colleagues wrote. “Adolescence provides a unique opportunity to examine risk factors for depression before the marked increase in disorder incidence and symptoms, especially in girls, who exhibit the sharpest rise in risk.”