Lurasidone lowered rates of weight, metabolic changes in bipolar depression

  • May 23, 2013

SAN FRANCISCO — Positive results were found in two pivotal safety and efficacy studies that looked at lurasidone HCl treatment in patients with depressive disorders associated with bipolar I disorder.

In the PREVAIL 1 study, 348 patients with bipolar depression were assigned lurasidone HCl (Latuda, Sunovion Pharmaceuticals; 20 mg/day to 120 mg/day) with or without rapid cycling as adjunctive therapy to lithium or valproate for 6 weeks. Metabolic changes in lipids, glucose, weight and insulin were assessed.

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  • CME Article
  • Cardiometabolic Health in Bipolar Disorder

  • Psychiatric Annals, May 2012, Volume 42 Issue 5
  • Describe the shared pathophysiology that contributes to the development of both bipolar disorder and cardiometabolic disease.
    Recognize genetic variants...More »

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