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Efficacy of ITI-007 for schizophrenia did not surpass placebo

Efficacy of ITI-007 for schizophrenia did not surpass placebo
September 29, 2016

Results from a second phase 3 clinical trial indicated ITI-007, an oral investigational treatment for schizophrenia, was not superior to placebo, while the active control risperidone was superior, according to a press release from Intra-Cellular Therapies.

“It is not uncommon in the field of psychiatry for studies to be challenged by high placebo response and there has been great variability in the effects observed from one study to the next,” Christoph Correll, MD, professor of psychiatry at Hofstra Northwell School of Medicine, said in the release. “Taken together, the ITI-007 schizophrenia program supports ITI-007 as a unique medication with an unprecedented safety and tolerability profile.”

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