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Research shows minimal efficacy of deep brain stimulation for treatment-resistant depression

July 30, 2015

Results from the first large-scale, randomized, sham-controlled trial of deep brain stimulation for treatment-resistant depression did not indicate significant efficacy at the end of the 16-week controlled phase.

“More recently, [deep brain stimulation] has been investigated as a potential neurosurgical intervention for psychiatric patients with obsessive-compulsive disorder (OCD) and [treatment-resistant depression]. Relying on the same devices and procedures used to treat movement disorders and OCD, different research groups have investigated the potential antidepressant efficacy of [deep brain stimulation] at various anatomical targets including the ventral capsule/ventral striatum (VC/VS), subgenual cingulate cortex (Cg25), nucleus accumbens, medial forebrain bundle, and lateral habenula,” Darin D. Dougherty, MD, of Massachusetts General Hospital and Harvard Medical School, and colleagues wrote.

In the Journals

Poverty linked to reduced brain development in children

July 29, 2015
Children from families living below the federal poverty level are at risk for reduced development of gray matter in the frontal and temporal lobes, according to recent…
In the Journals

Teens medically prescribed marijuana more likely to report addiction

July 29, 2015
High school seniors using marijuana for medical reasons were 10 times more likely to report addiction to the drug than peers who obtain marijuana illegally, according to…
In the JournalsPerspective

Health care spending expected to increase over decade, but at historically low rate

July 29, 2015
Due to expanded health insurance coverage from the ACA, as well as the aging population and economic growth, health care spending is projected to increase at a rate of…
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Geriatric Psychopharmacology: Pharmacokinetic and Pharmacodynamic Considerations

Psychiatric Annals, July 2015, Volume 45 Issue 7
Older adults represent the fastest growing demographic in both developing and developed countries. Understanding…
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Journal of Psychosocial Nursing and Mental Health Services June 2015 CNE Activity

This activity is co-provided by Villanova University College of Nursing and SLACK Incorporated.

Topics include checklist for delirium, stress in first-year nursing students, and mantram repetition for insomnia.
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Meeting News Coverage Video
VIDEO: Mental health needs more attention in management of diabetes

VIDEO: Mental health needs more attention in management of diabetes

June 10, 2015
BOSTON — In this video exclusive, David G. Marrero, PhD, the 2015 President for Health and Education of the…
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