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Impulse control disorders linked to dopamine receptor agonists

October 21, 2014

Pathological gambling, hypersexuality, compulsive shopping and other impulse control disorders were associated with the use of dopamine receptor agonists, often prescribed for Parkinson’s disease, restless leg syndrome and hyperprolactinemia, according to new research.

Investigators identified 1,580 reports of serious impulse control issues reported as adverse events in the FDA’s Adverse Event Reporting System database (FAERS) between 2003 and 2012 and calculated the proportional reporting ratio (PRR) to dopamine receptor agonists. The median age of the patients (65.8% men) was 55 years, and 48.3% of the reported events occurred outside the United States.

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Follow a checklist to help decide what to do with estate life insurance

October 20, 2014
Before recent changes in estate laws, it was common for attorneys, financial planners and insurance agents to recommend purchasing life insurance — commonly called…
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FDA approves new labeling for extended-release Embeda

October 20, 2014
The FDA has approved new labeling for an extended-release pain relief combination of morphine sulfate and naltrexone hydrochloride that includes information on potential…
figure Health Care Updates

Open Payments search tool released

October 20, 2014
CMS announced it has added a simple search tool to its Open Payments website, which now includes more detailed information.Users can search the database in three ways…
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Suvorexant: A Novel Therapy for the Treatment of Insomnia

Journal of Psychosocial Nursing and Mental Health Services, October 2014, Volume 52 Issue 10
Suvorexant is a pharmacologically novel dual antagonist of orexin receptors OX1R and OX2R, which has an effect that…
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Is There a Changing Paradigm in the Management of Bipolar Depression? An Evidence-based Approach to Help Define Treatment Options

This activity is supported by an educational grant from Sunovion Pharmaceuticals, Inc.

Signs and symptoms of bipolar disorder are diverse and include, but are not limited to, impulsive behavior…
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Experts debate PANDAS diagnosis in children

September 18, 2014
WASHINGTON, D.C. — Margaret K. Hostetter, MD, the B. K. Rachford professor and chair of department of…
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