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Reducing antipsychotic dosage feasible, effective among patients with late-life schizophrenia

July 1, 2015

Results from an open-label, single-arm prospective study indicate that reducing dosage of antipsychotics is feasible among patients with late-life schizophrenia and can improve extrapyramidal symptoms, hyperprolactinemia and other symptoms related to increases in dopamine D2/3 receptor occupancies.

“Schizophrenia is a life-long illness that typically requires maintenance antipsychotic treatment throughout an individual’s life… Clinical guidelines developed by expert consensus recommend the use of lower doses of antipsychotics in older patients with schizophrenia. However, empirical data on age-specific antipsychotic dosing are limited,” study researcher Ariel Graff-Guerrero, MD, PhD, of the Centre for Addiction and Mental Health in Toronto, and colleagues wrote.

In the Journals

Obese teens found less likely to use oral contraceptives

July 1, 2015
Contraception, especially oral contraception, is significantly less likely to be used by obese adolescents, compared with adolescents of normal weight, according to…
Mark Olfson, MD, MPH In the Journals

Antipsychotics may be excessively, unnecessarily prescribed to adolescents

July 1, 2015
Results from a population-level, retrospective, observational study suggest that much of the antipsychotic use among children in the United States targets limited…
Bradley Stein In the Journals

Waiver program approving office-based buprenorphine treatment may increase access to opioid addiction treatment

July 1, 2015
Recent analysis in Health Affairs showed that as the number and geographic distribution of physicians with waivers allowing them to provide office-based…
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CNE Article

Mantram Repetition Program Decreases Insomnia Among Homeless Women: A Pilot Study

Journal of Psychosocial Nursing and Mental Health Services, June 2015, Volume 53 Issue 6
The current pre-/posttest pilot study recruited homeless women from “safe” car parks and transitional…
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JPN May 2015

Journal of Psychosocial Nursing and Mental Health Services May 2015 CNE Activity

This activity is co-provided by Villanova University College of Nursing and SLACK Incorporated.

Topics include therapeutic doll play, military nurses’ reintegration, and synthetic cannabinoids.
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Meeting News Coverage Video
VIDEO: Mental health needs more attention in management of diabetes

VIDEO: Mental health needs more attention in management of diabetes

June 10, 2015
BOSTON — In this video exclusive, David G. Marrero, PhD, the 2015 President for Health and Education of the…
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