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Use of minimally invasive markers for airway eosinophilia in asthma detection ineffective

March 27, 2015

The use of fractional exhaled nitric oxide, blood eosinophils and immunoglobulin E as a single surrogate marker for airway eosinophilia in patients with asthma may lead to a notable number of false positives or false negatives, according to study results.

“Based on our findings, we discourage the use of (fractional exhaled nitric oxide [FeNO]), blood eosinophils, or (immunoglobulin E [IgE]) as single surrogate tests for detecting airway eosinophilia in asthma,” Daniël A Korevaar, MD, of the University of Amsterdam, and colleagues wrote. “Our meta-analyses show that, at the optimal cutpoint, sensitivities and specificities of these markers for detecting sputum eosinophilia are moderate.”

Breaking News

Senate adjourns without voting on bill to repeal sustainable growth rate

March 27, 2015
The U.S. Senate left for its 2-week spring break without voting on a bill that repeals the sustainable growth rate, leaving physicians to face a 21% payment cut if…
In the Journals

CD4 cell counts rebound among most children treated for HIV

March 27, 2015
Data from an NIH-funded study in AIDS suggest the majority of children with HIV eventually recover their CD4 cell levels after undergoing virologic…
Meeting News Coverage

Researcher of study on SCFE patients highlights importance of early weight management

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LAS VEGAS — A 20-year follow-up of pediatric patients who underwent in-situ fixation for slipped capital femoral epiphysis shows many patients had poor health and…
Caregivers frequently unaware of safety guidelines for young baseball pitchers Meeting News Coverage

Caregivers frequently unaware of safety guidelines for young baseball pitchers

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LAS VEGAS — Results of a survey presented at the American Academy of Orthopaedic Surgeons Annual Meeting indicated caregivers were frequently unaware of safety…
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Basic Science Tidbit

ICAM Still Roll With It

Journal of Pediatric Ophthalmology and Strabismus, March/April 2015, Volume 52 Issue 2
No abstract available for this article.
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Pediatric Annals January 2015

Unusual Diagnoses: Part 1: January 2015

Keck School of Medicine of USC and Pediatric Annals

Index of suspicion—a term used daily by clinicians in general practice who must, in a sea of “normal”…
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Meeting News Coverage Video
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VIDEO: Recent research promises breakthroughs in pediatric care

March 10, 2015
SAN DIEGO — In this video exclusive, Mark A. Sperling, MD, emeritus profess of pediatrics and endocrinology and…
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