Top Story

CHOP investigating safety of PEG 3350 for constipation in children

January 27, 2015

The Children’s Hospital of Philadelphia is investigating the safety of polyethylene glycol 3550 for treatment of constipation in the pediatric population, according to a press release.

The FDA-funded study aims to determine if certain components of PEG 3350 that are present in over-the-counter medications commonly prescribed for constipation in children are absorbed into the bloodstream, and if so, whether it causes adverse effects, the release explained. According to the NIH website, these components include “low molecular weight (LMW) species that may be found in PEG 3350 products (e.g., ethylene and diethylene glycol) and … PEG 3350 metabolites.” Although chronic use of PEG 3350 and use in children younger than 17 years is not approved by the FDA, it is used as such in clinical practice, according to the website.

Clusters of underimmunized, vaccine-refusal communities identified in California

January 27, 2015
Underimmunized communities and families that refuse vaccines were found to cluster geographically, which could significantly increase the risk for an outbreak and create…
In the Journals

Altered gait, biomechanics seen in patients with juvenile fibromyalgia

January 27, 2015
Patients with juvenile fibromyalgia showed alterations in walking patterns, greater knee weakness, lower bilateral hip abduction strength, reduced ankle dorsiflexion and…
In the Journals

Most pro-marijuana tweets involved those aged younger than 25 years

January 26, 2015
Study findings published in the Journal of Adolescent Health indicate the majority of tweets about marijuana were sent and received by Twitter users aged younger than…
In the Journals

Child's death linked to N. fowleri in treated tap water

January 26, 2015
A case of primary amebic meningoencephalitis that led to the death of a child in Louisiana was associated with culturable Naegleria fowleri in tap water from a treated…
More News Headlines »
Guest Editorial

Common Signs and Symptoms and Unusual Diagnoses: Part 1

Pediatric Annals, January 2015, Volume 44 Issue 1
More »
Pediatric Annals December 2014

Sports Medicine: December 2014

Keck School of Medicine of USC and Pediatric Annals

The past two decades have witnessed an amazing increase in the participation in competitive sports by children of all…
More »
Meeting News Coverage Video
thumbnail for video 3918683373001

Lessons every clinician should know about lymphadenopathy and lymphadenitis

December 5, 2014
NEW YORK — Mary Anne Jackson, MD, chief of the Pediatric Infectious Diseases section at Children’s Mercy…
More »