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Intermittent montelukast for children with wheeze produced no clear benefit

November 25, 2014

Intermittent montelukast in young children with wheeze showed no significant benefit when compared with placebo, according to study results.

Researchers conducted a parallel-group, randomized trial between October 2010 and December 2013 at 21 primary care sites and 41 secondary care sites in England and Scotland. There were 1,358 children aged 10 months to 5 years with two or more wheeze episodes allocated to receive a 5/5 or 5/x+x/x arachidonate 5-lipoxygenase (ALOX5) gene promoter “then randomly assigned (1:1) via a permuted block schedule (size ten), to receive intermittent montelukast [n=669] or placebo [n=677] … at each wheeze episode over a 12-month period.”

Meeting News Coverage

Inadequate contact lens hygiene increased risk for acute conjunctivitis

November 25, 2014
NEW YORK — Failure to properly clean and store contact lenses significantly increased risk for acute conjunctivitis, according to a presenter at the 2014…
New AAP guidance revisions impact palivizumab prophylaxis for RSV Meeting News CoverageVideo

New AAP guidance revisions impact palivizumab prophylaxis for RSV

November 24, 2014
NEW YORK — H. Cody Meissner, MD, an Infectious Diseases in Children Editorial Board member, discusses the AAP’s Red Book Committee updated guidance for use…
NAFLD associated with high BP, hypertension in children In the Journals

NAFLD associated with high BP, hypertension in children

November 24, 2014
Pediatric patients with nonalcoholic fatty liver disease were more likely to have high blood pressure and persistent high blood pressure compared with children without…
Carla Davis, MD In the Journals

School nurse program increased epinephrine availability to students

November 24, 2014
A training program for school nurses in Houston decreased students’ reactions to food allergies and increased student-specific injectable devices, according to…
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Original Article

Congenital Nasolacrimal Duct Obstruction: Common Management Policies Among Pediatric Ophthalmologists

Journal of Pediatric Ophthalmology and Strabismus
Online Advanced Release, November 4, 2014
To study common management policies of congenital nasolacrimal duct obstruction (CNDLO) among pediatric…
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CME
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Updates in Systemic Juvenile Idiopathic Arthritis: What New Guidelines Mean to Your Practice

This activity is supported by an educational grant from Genentech, Inc.

Systemic juvenile idiopathic arthritis (JIA) accounts for 5% to 15% of patients diagnosed with JIA and is the most…
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Meeting News Coverage Video
Lack of effective strategies available to address vaccine-hesitant parents

Lack of effective strategies available to address vaccine-hesitant parents

November 23, 2014
NEW YORK — Sean T. O'Leary, MD, MPH, from the department of pediatrics at the University of Colorado, discusses…
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