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Higher doses of vancomycin linked to kidney injury in children

January 29, 2015

Acute kidney injury was common among hospitalized children who received vancomycin, with higher doses associated with an increased risk for kidney damage, according to study data.

“Recently published Infectious Diseases Society of America treatment guidelines for methicillin-resistant Staphylococcus aureus infections recommend vancomycin 15 mg/kg/dose every 6 hours in children with serious or invasive disease, and commonly used dosing references now also recommend higher dosing,” Elizabeth A. Sinclair, PharmD, of Texas Children’s Hospital in Houston, and colleagues wrote.

Ravi M. Patel, MD, MSc In the Journals

Mortality declined among extremely premature infants

January 28, 2015
The rates of overall mortality decreased among extremely premature infants from 2000 through 2011, specifically infant deaths ascribed to bronchopulmonary dysplasia and…

Obama administration proposes $1.2 billion of antibiotic resistance-related funding

January 28, 2015
The Obama administration’s 2016 fiscal year budget proposal includes more than $1.2 billion of federal funding toward combating antibiotic resistance, according…
In the Journals

Study links facial port-wine stain patterns with Sturge-Weber syndrome risk

January 28, 2015
Specific upper-facial port-wine stain patterns in infants were associated with an increased risk of Sturge-Weber syndrome, according to recently published study…
Peter Szatmari In the Journals

ASD symptom severity differences increased by age 6 years

January 28, 2015
Only a small portion of developmental trajectories in autism spectrum disorder severity and adaptive functioning occurs during the preschool years, suggesting that some…
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Firm Rounds

A 2-Year-Old Male with Persistent Fever and Pneumonia

Pediatric Annals, January 2015, Volume 44 Issue 1
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Pediatric Annals November 2014

Child Neglect: November 2014

Keck School of Medicine of USC and Pediatric Annals

Neglect, to paraphrase, is in the eyes of the beholder. While a special needs child may not receive optimal care at…
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Lessons every clinician should know about lymphadenopathy and lymphadenitis

December 5, 2014
NEW YORK — Mary Anne Jackson, MD, chief of the Pediatric Infectious Diseases section at Children’s Mercy…
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